Flavonoids are a type of plant metabolite that are widely distributed throughout the plant kingdom. Within this group of compounds, flavones are a particularly interesting subgroup due to their unique structural features and potential health benefits.

The basic scaffold of flavones consists of two aromatic rings (A and B rings) connected by a three-carbon chain (C ring). Flavones are characterized by having a double bond between positions 2 and 3 on their C ring and lacking a hydroxyl group on position 3. These structural features are thought to be important for the biological activity of flavones, including their antioxidant and anti-inflammatory effects.

One of the most well-known sources of flavones is parsley, which is known for its high polyphenol content. In fact, a study conducted on the flavonoid content of parsley found that it contains a significant amount of flavones, specifically apigenin and luteolin.  [1]Other sources of flavones include celery, thyme, and chamomile.

The health benefits of flavones have been the subject of much research in recent years. Studies have suggested that flavones can help to reduce inflammation throughout the body, which may be beneficial for conditions such as arthritis and asthma. [2] In addition, flavones may have antioxidant properties that can help to protect cells from damage caused by free radicals. Free radicals are unstable molecules that can damage cells and contribute to the development of chronic diseases like cancer and heart disease. [3]

One study conducted on the potential cardiovascular benefits of flavones found that they may help to reduce the risk of coronary heart disease by improving blood flow and reducing inflammation. [4]

Another area of research on flavones has focused on their potential anti-cancer effects. Studies have suggested that flavones can interfere with the growth and spread of cancer cells, potentially reducing the risk of certain types of cancer. [5] One study conducted on the effects of apigenin, a flavone found in parsley and other plants, found that it was able to inhibit the growth of cancer cells in vitro. [6] While more research is needed in this area, these findings suggest that flavones may be a promising area of research for cancer prevention and treatment.

Overall, flavones are a unique and fascinating subgroup of flavonoids that have shown promising health benefits in a variety of areas. From reducing inflammation to protecting against cancer, flavones have the potential to play an important role in human health. While more research is needed to fully understand their mechanisms of action and potential applications, the future looks bright for these remarkable compounds. So the next time you’re searching for ways to improve your health, be sure to consider incorporating flavone-rich foods like parsley, celery, and thyme into your diet.

Flavonoids are powerful compounds found in many natural foods that offer a range of potential health benefits.

Flavonoids found in foods:

1. Quercetin – found in vegetables, fruits, and beverages like spices, soups, and fruit juices, possessing anti-inflammatory and antioxidant properties.
2. Rutin – found in green tea, grape seeds, red pepper, apple, citrus fruits, berries, and peaches, having antioxidant and anti-inflammatory potential.
3. Macluraxanthone – found in Maclura tinctoria (Hedge apple) and Dyer’s mulberry, offering anti-inflammatory and antitumor potential.
4. Genistein – found in numerous plant-based sources such as soybeans, red clover, and kudzu, offers anti-inflammatory and antioxidant properties.
5. Scopoletin – found in vinegar and dandelion coffee, possessing antioxidant, antibacterial, and anti-inflammatory properties.
6. Daidzein – found in soybeans and tofu offers anti-inflammatory and immune modulating benefits.
7. Taxifolin – found in vinegar and citrus fruits, offering antitumor, anti-inflammatory, and antioxidant properties.
8. Naringenin – found in grapes, possessing antioxidant and anti-inflammatory properties.
9. Abyssinones – found in French bean seeds, offers moderate antioxidant and antitumor effects.
10. Rutin – found in citrus fruits, apple, berries, and peaches, possessing antioxidant and anti-inflammatory properties.
11. Eriodictyol – found in lemons and rosehips, offers anti-inflammatory and anticancer benefits.
12. Fisetin – found in strawberries, apples, persimmons, onions, and cucumbers, offers anti-inflammatory and antitumor properties.
13. Theaflavin – found in tea leaves, black tea, and oolong tea, offers anti-inflammatory, antibacterial, and antioxidant properties.
14. Peonidin – found in cranberries, blueberries, plums, grapes, cherries, and sweet potatoes, possesses antioxidant and anti-inflammatory properties.
15. Diosmetin – found in vetch, possessing potential antihypertensive and anti-inflammatory properties.
16. Tricin – found in rice bran, possessing antioxidant, antihypertensive, antihyperglycemic properties.
17. Biochanin – found in red clover, soya, alfalfa sprouts, peanuts, and chickpeas (Cicer arietinum), offers anti-inflammatory and immune-modulating benefits.
18. Hesperidin – found in bitter orange, petit grain, orange, orange juice, lemon, and lime, offers anti-inflammatory, antitumor, and antioxidant benefits.
19. Epicatechin – found in milk and chocolate, offers anti-inflammatory, antitumor, and antiplatelet effects.
20. Myricetin – found in vegetables, fruits, nuts, berries, tea, and red wine, offers anti-inflammatory, antitumor, and antioxidant benefits.
21. Taxifolin – found in citrus fruits, possesses potential antioxidant and anti-inflammatory properties.
22. Kaempferol – found in apples, grapes, and vegetables like broccoli, spinach, and green beans, offers anti-inflammatory and anticancer properties.
23. Luteolin – found in celery, broccoli, and other vegetables, possesses anti-inflammatory, antitumor, and antioxidant properties.
24. Apigenin – found in milk and chocolate, possessing potential antianxiety and antioxidant properties.

Including these natural foods in your regular diet could provide numerous health benefits, including reducing inflammation, preventing chronic diseases, and supporting overall health and wellness.

Table information source